These days, odds are that you have/had cancer, or know somebody who does. It is known that approximately one million Canadians that were alive at the beginning of 2009 have had cancer diagnosis in last 10 years. It’s estimated that two out of every five Canadians will get cancer diagnosis within their life time, and one in every four will die. Also in United States, one out of every two men, and one out of every three women will get cancer diagnosis.

Since the scientists started recording, these rates have continued to skyrocket and more people are asking questions and become interested about the environment we choose to surround ourselves with, on a daily basis.

Radiation and chemotherapy are the only two approved treatments for cancer and new research is emerging everyday that puts into question these two methods. It looks like the medical community is forced to embrace new options when it comes to cancer treatment. Chemotherapy fuels the cancer growth, which is known to the scientists, yet nothing has been changed, both methods are excessively toxic to the human body.

A little Chinese herb might be added in the growing list of cancer killers via alternative methods of treatment. In compliance of studies published in Life Sciences, Cancer Letters and Anticancer Drugs, artemesinin, which is a derivate of the wormwood plant commonly used in Chinese medicine, is capable to kill cancer cells, at a rate of 12,000 cancer cells for every healthy cell.

Henry Lai and his team of researchers from the University of Washington synthesized the composite, which uses a cancer cells appetite for iron to make them the target. Artemisinin can selectively kill cancer cells while normal cells are unharmed.

“By itself, artemisinin is about 100 times more selective in killing cancer cells as opposed to normal cells. Artemisinin is 34,000 times more potent in killing the cancer cells as opposed to their normal cousins. So the tagging process appears to have greatly increased the potency of artemisinin’s cancer-killing properties”– says Henry Lai.

The composite is licensed to Holley Pharmaceuticals, but it hasn’t been used for cancer treatment in humans.

“We call it a Trojan horse because the cancer cell recognizes transferrin as a natural, harmless protein. So the cell picks up the composite without knowing that a bomb (artemisinin) is hidden inside” – says Henry Lai.

Many centuries ago the wormwood extract is used for healing purposes. The treatment has been rediscovered in an ancient manuscript that contains medical remedies. Killing 12,000 cancer cells for every healthy cell, it could be turned into a drug with minimal side effects.

“The composite is currently being licensed by the University Of Washington To Artemisia Biomedical Inc., a company founded in Newcastle, Washington by Lai, Sasaki and Narendra Singh, UW associate professor of bioengineering, for development and commercialization. Human tests are at least several years away. Sasaki said that artemisinin is readily available, hoping that their composite can be cheaply manufactured making it affordable for the patients in developing countries.”

The abstracts read:

“Artemisinin is forming radicals that kill cells, reacting with iron. Cancer cells uptake relatively larger amounts of iron than normal cells, making them more liable to the toxic effect. In previous research we have shown that artemisinin is more drawn to cancer cells than to normal cells. In the present research, we covalently attached artemisinin to the iron – carrying plasma glycoprotein transferrin. Transferrin is transported into the cells via receptor – mediated endocytosis and cancer cells express significantly more transferrin receptors on their cell surface and endocytose more transferring than normal cells. Thus, we hypothesize that both iron and artemisinin would be transported into cancer cells in one package, by tagging artemisinin to transferrin. Once inside a cell, iron will be released and can readily react with artemisinin close by tagged to the transferrin, enhancing the toxicity and selectivity of artemisinin towards cancer cells. We found that holotransferrin-tagged artemisinin, compared with artemisinin, is very potent and selective in killing cancer cells. Thus, this ‘tagged – composit’ could potentially be developed into an effective chemotherapeutic agent for cancer treatment.”

Another abstract reads:

“We found that the artemisinin disruption of E2F1 transcription factor expression mediates the cell cycle arrest of human breast cancer cells and represents a critical transcriptional pathway by which artemisinin controls human reproductive cancer cell growth.”

FDA approved artemisinin for the treatment of malaria; also it’s very safe and easy to use. Though it’s inexpensive and works on all cancers has yet to find its way into the mainstream. It’s time to replace radiation, surgery and chemotherapy for the treatment of cancer.

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These days, odds are that you have/had cancer, or know somebody who does. It is known that approximately one million Canadians that were alive at the beginning of 2009 have had cancer diagnosis in last 10 years. It’s estimated that two out of every five Canadians will get cancer...